Peptide index

The seven-residue behaviourally active core of ACTH, stripped of its steroid-releasing activity, studied for decades for attention and memory and best known now as the fragment Semax was built from.

Cognitive & Nootropic

An enzymatically digested porcine brain extract of low-molecular-weight neuropeptides and free amino acids, given by injection or infusion in Europe and Asia for stroke, traumatic brain injury and dementia.

Cognitive & Nootropic

A bovine cerebral cortex peptide extract given intramuscularly in Russian neurology for encephalopathy, post-stroke recovery, childhood developmental delay and cognitive decline.

Cognitive & Nootropic

A peripherally restricted leu-enkephalin analogue used in Russian medicine for pancreatitis, peptic ulcer and surgical stress protection, which does not cross the blood-brain barrier and therefore does not get you high.

Cognitive & Nootropic

An eight-residue fragment of activity-dependent neuroprotective protein that stabilises microtubules and reduces tau hyperphosphorylation, and which failed a large phase 3 trial in progressive supranuclear palsy.

Cognitive & Nootropic

A blood-brain-barrier-penetrant angiotensin IV derivative that potentiates hepatocyte growth factor at the c-Met receptor and, in rodents, drives synapse formation orders of magnitude more potently than BDNF.

Cognitive & Nootropic

A 15-residue mimetic of the neural cell adhesion molecule's FG loop that activates FGF receptor 1 and promotes synaptogenesis and memory consolidation in rodents.

Cognitive & Nootropic

Terminally capped Selank that lasts longer per dose, used for all-day anxiolysis without sedation or dependence.

Cognitive & Nootropic

A terminally capped version of Semax that resists breakdown for longer, so it hits harder per milligram and lasts through a working day instead of a morning.

Cognitive & Nootropic

A 20-residue neuropeptide with the unusual property of increasing wakefulness and arousal while simultaneously reducing anxiety - a combination almost nothing else in pharmacology achieves.

Cognitive & Nootropic

An orally active dipeptide nootropic registered in Russia that raises NGF and BDNF in the hippocampus and is used for memory, attention and post-injury cognitive recovery.

Cognitive & Nootropic

The hypothalamic wakefulness neuropeptide whose loss causes narcolepsy, given intranasally in research settings to restore alertness and working memory after sleep deprivation.

Cognitive & Nootropic

A nine-amino-acid posterior pituitary hormone taken intranasally for social ease, trust and emotional connection, with an obstetric role that has nothing to do with why people in this space use it.

Cognitive & Nootropic

An adamantylated four-residue fragment of ciliary neurotrophic factor that boosts hippocampal neurogenesis and BDNF and reduces tau pathology in Alzheimer's models.

Cognitive & Nootropic

A shortened spadin analogue that blocks the TREK-1 potassium channel and produces antidepressant effects in rodents within days rather than the weeks an SSRI takes.

Cognitive & Nootropic

Tuftsin-derived anxiolytic peptide registered in Russia for generalised anxiety that takes the edge off without sedation, cognitive fog, or the dependence and withdrawal that come with benzodiazepines.

Cognitive & Nootropic

Russian-registered ACTH(4-10) analogue taken intranasally for focus, mental stamina and post-stroke recovery, which raises BDNF and NGF without any of the cortisol-releasing activity of the parent hormone.

Cognitive & Nootropic