Peptide index

331 compounds across 19classes. Each one carries an evidence tier, because “there are studies” means something very different for semaglutide than it does for most of this list.

Ctrl K

16 compounds

Cetrorelix
Approved drug
A GnRH antagonist that blocks the premature LH surge in IVF cycles immediately, with no flare and no waiting period.
Sexual Health, Melanocortin & Reproductive
Degarelix
Approved drug
A GnRH antagonist that drops testosterone to castrate levels within three days and, unlike the agonist depots, never causes a hormone flare.
Sexual Health, Melanocortin & Reproductive
Follitropin alfa/beta
Approved drug
Recombinant follicle-stimulating hormone, the workhorse of ovarian stimulation and, paired with hCG, the drug that actually restores sperm production in men.
Sexual Health, Melanocortin & Reproductive
Ganirelix
Approved drug
A third-generation GnRH antagonist supplied in a ready-to-use prefilled syringe, doing the same job as cetrorelix in IVF with no mixing step.
Sexual Health, Melanocortin & Reproductive
Gonadorelin
Approved drug
Native gonadotropin-releasing hormone, used in short pulses to keep the testes signalling and working while on testosterone replacement.
Sexual Health, Melanocortin & Reproductive
Goserelin
Approved drug
A GnRH agonist delivered as a small biodegradable rod pushed under the skin of the abdomen, giving one or three months of hormone suppression per implant.
Sexual Health, Melanocortin & Reproductive
hCG
Approved drug
A placental hormone that acts as a long-acting LH substitute, used to keep the testes producing testosterone and sperm during or after testosterone replacement and steroid use.
Sexual Health, Melanocortin & Reproductive
Histrelin
Approved drug
A GnRH agonist in a hydrogel implant that sits under the skin of the inner arm and suppresses sex hormones for a full year on one insertion.
Sexual Health, Melanocortin & Reproductive
Kisspeptin-10
Human trials
The hypothalamic switch that sits upstream of GnRH, used to kick the whole reproductive axis into gear and, in imaging studies, to increase sexual and emotional brain responses.
Sexual Health, Melanocortin & Reproductive
Kisspeptin-54
Human trials
The full-length kisspeptin isoform, used in IVF research as an oocyte-maturation trigger that carries far less ovarian hyperstimulation risk than hCG.
Sexual Health, Melanocortin & Reproductive
Leuprolide
Approved drug
The most widely used GnRH agonist depot in the world, producing near-complete chemical castration after an initial hormone flare.
Sexual Health, Melanocortin & Reproductive
Melanotan I
Approved drug
A linear alpha-MSH analogue that tans the skin through MC1R without the nausea, flushing and erections of Melanotan II, and is genuinely approved as an implant for a rare light-sensitivity disease.
Sexual Health, Melanocortin & Reproductive
Melanotan II
Human trials
A non-selective melanocortin agonist that produces a deep, genuine tan with very little sun exposure, and drags strong libido and appetite suppression along with it whether you wanted them or not.
Sexual Health, Melanocortin & Reproductive
Nafarelin
Approved drug
A GnRH agonist given as a nasal spray, which makes it the needle-free option for endometriosis and early puberty suppression.
Sexual Health, Melanocortin & Reproductive
PT-141
Approved drug
An FDA-approved melanocortin agonist that raises sexual desire and arousal from the brain rather than by opening blood vessels, so it works on wanting sex rather than on plumbing.
Sexual Health, Melanocortin & Reproductive
Triptorelin
Approved drug
A potent GnRH agonist used as a depot to shut down sex hormones in prostate cancer and endometriosis, and used off-label as a single low-dose shot to try to restart a suppressed testosterone axis.
Sexual Health, Melanocortin & Reproductive