Peptide index

A liver- and brain-secreted peptide that tells the body whether to burn carbohydrate or fat and keeps the vascular endothelium healthy; low levels track with insulin resistance and cardiovascular disease in humans.

Emerging & Frontier Research

A 12-amino-acid peptide found by an AI prohormone-cleavage screen at Stanford that cuts food intake by up to half in rodents and pigs through hypothalamic POMC neurons, apparently without the nausea that limits GLP-1 drugs.

Emerging & Frontier Research

A somatostatin cousin that binds every somatostatin receptor but also hits the ghrelin and MRGPRX2 receptors, giving it a genuinely distinct profile in slow-wave sleep, inflammation and fibrosis.

Emerging & Frontier Research

Plant peptides with a head-to-tail cyclic backbone locked by a knotted disulfide core, so stable they survive boiling and gut proteases — used as scaffolds to make other peptides orally bioavailable rather than as drugs themselves.

Emerging & Frontier Research

Peptides and small proteins invented from nothing by diffusion models rather than found in nature, now routinely producing picomolar-to-nanomolar binders against targets that had no drug-like chemistry at all.

Emerging & Frontier Research

Cell-derived nanovesicles loaded with or displaying regenerative peptides, used to get cargo across barriers that free peptides cannot cross — scientifically real, commercially a swamp.

Emerging & Frontier Research

The brainstem stress signal that causes profound appetite loss — being pushed as an agonist for obesity and blocked as an antagonist for cancer cachexia, with the antagonist side now the more convincing of the two.

Emerging & Frontier Research

The exercise-released myokine that browns white fat and is linked to bone density and cognitive protection — a decade-long scientific brawl over whether it exists that has largely resolved in its favour.

Emerging & Frontier Research

Short fragments of the anti-aging protein Klotho engineered to reproduce its cognitive and kidney-protective effects in a molecule small enough to actually manufacture and dose.

Emerging & Frontier Research

Bacterially produced peptides physically threaded through their own macrolactam ring like a slipknot, giving protease and heat stability that no ordinary peptide has — currently the most interesting new antibiotic scaffold in years.

Emerging & Frontier Research

Constrained cyclic peptides selected from trillion-member mRNA-display libraries and chemically tuned to survive the gut — the technology that produced enlicitide, the first oral PCSK9 inhibitor, approved in July 2026.

Emerging & Frontier Research

A BASF cosmetic ingredient launched in 2026 that adapts collagen-hybridizing-peptide chemistry so the peptide binds only where collagen is already damaged, concentrating repair signalling at the sites that need it.

Emerging & Frontier Research

A hypothalamic satiety peptide that suppresses food intake completely independently of leptin, which is why it keeps getting revisited as a route into leptin-resistant obesity.

Emerging & Frontier Research

A gut and brain neuropeptide that suppresses appetite and simultaneously raises energy expenditure, now being engineered into long-acting analogues as a combination partner for incretins.

Emerging & Frontier Research

The bone-secreted hormone that turns out to talk to muscle, pancreas, testis and brain — proposed as the signal that lets the skeleton coordinate exercise capacity, glucose handling and fertility.

Emerging & Frontier Research

Single molecules engineered to hit four or more metabolic receptors at once — GLP-1, GIP, glucagon and amylin — chasing greater weight loss with better lean-mass retention and less nausea than any one pathway allows.

Emerging & Frontier Research

A 14-amino-acid galanin-family peptide that is dramatically suppressed in obesity and, when given back to animals, reduces food intake and improves lipid handling.

Emerging & Frontier Research

Non-pharmacy incretin supply sold as 'research chemicals' — the same molecule on paper as Mounjaro, with none of the identity, purity, sterility or concentration guarantees, and the single biggest source of real-world harm in the 2026 peptide space.

Emerging & Frontier Research